Effect of intraoperative dexmedetomidine on postoperative ileus of parturient after cesarean section under combined spinal and epidural anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068136

Enrollment

Unknown

Registered

2023-02-08

Start date

2023-02-15

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Interventions

experimental group:dexmetomidine

control group:normal saline

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.parturient women undergoing cesarean section of the scarred uterus under combined spinal and epidural anesthesia; 2. Subjects aged 18-40 and weighing 45-90kg; 3. American Society of anesthesiologists (ASA) grade II.

Exclusion criteria

Exclusion criteria: Patients without a history of cesarean section; Patients with severe hepatic and renal insufficiency before operation; Intraspinal anesthesia contraindicated; Patients with preoperative bowel function problems; Patients with a history of severe bradycardia and heart block; Patients with severe liver and kidney dysfunction; Patients with mental disorders; Patients with severe hypertension; Patients allergic to dexmedetomidine and related ingredients; Other researchers think it is not suitable for the situation of this study.

Design outcomes

Primary

Measure	Time frame
time to first flatus;	—

Secondary

Measure	Time frame
time to first feces;pain scores;postoperative nausea and vomiting;Postoperative quality of recovery QoR-40 score;hospital length of stay;	—

Countries

China

Contacts

Public ContactLu bin

Ruian People's Hospital

ralubin@126.com13967746847

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026