cognitive frailty
Conditions
Interventions
Control group:Multi-cognitive-domain cognitive training
Experimental group:Single-cognitive domain memory training
Sponsors
School of Nursing, Southern Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Aged = 60 years old; 2. Continue to live in the pension institution for at least 3 months; 3.Reversible cognitive frailty: physical frailty (including pre-physical frailty) and cognitive impairment, in which physical frailty was judged by Fried scale score 1-5, and cognitive impairment was judged by Montreal Cognitive Assessment scale MoCA = 25; 4.Complaints of cognitive decline (mainly memory); 5.Regular exercise in the last six months. All inclusion criteria are met before inclusion.
Exclusion criteria
Exclusion criteria: 1.Hypertensive patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg); 2.History of alcohol and drug abuse; 3.Have a history of mental illness (such as personality disorder, schizophrenia, depression, etc.), or severe aphasia and audio-visual disorders, or severe organ failure, history of ventricular infarction, history of coronary heart disease, musculoskeletal disorders and other exercise contraindications; 4.Use of drugs that affect cognitive function (chololine enzyme inhibitors, memantine hydrochloride, cabalatine, antipsychotics, etc.) 5.Unwilling to participate in this study; 6.Participating in other clinical study and will affect the evaluation of the results of this study. Any of the above conditions are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reversal rate of cognitive frailty;global cognitive function;frailty; | — |
Secondary
| Measure | Time frame |
|---|---|
| physical function;memory and attention;executive function;quality of life; | — |
Countries
China
Contacts
Public ContactGao Yulin
School of Nursing, Southern Medical University
Outcome results
None listed