Post stroke depression
Conditions
Interventions
Paroxetine hydrochloride tablet group:Take paroxetine hydrochloride tablets orally, 1 tablet each time, once a day
Paroxetine hydrochloride tablet+self-designed Jieyu prescription group:On the basis of the treatment in the control group, the observation group drank self-designed Jieyu prescription: 1 dose a day, d
Cognitive behavioral therapy+self-designed Jieyu prescription group:On the basis of the treatment in the control group, the observation group drank self-designed Jieyu prescription: 1 dose a day, drin
Stroke patients without depression:Placebo treatment
Sponsors
Wenzhou Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? At the same time comply with the prescribed diagnostic standards of Chinese and western medicine; ? Those who agree and sign the informed consent; ? Age 18-80 years old; ? Have the ability of communication and expression; ? Hamilton Depression Scale (17 items) score in 8-24; ? Secondary to acute cerebrovascular disease 2 weeks later to 1 year.
Exclusion criteria
Exclusion criteria: ? Patients with severe aphasia or cognitive impairment;? People with a history of mental illness or suicide attempts; ? Unwilling to take Chinese medicine; ? Patients with digestive tract diseases that may affect the intestinal flora; ? Patients taking antibiotics in recent 2 months; ? At the same time accept other clinical trial patients; ? Hamilton Depression Scale (17 items) score =25: may have major depression patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale (17 items);TCM syndrome integration;6/5000 Self-Rating Depression Scale(SDS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor function (short Fugl-Meyer) score;Activities of Daily Living Score (ADL); Hamilton Anxiety Scale (HAMA);Intestinal flora; | — |
Countries
China
Contacts
Public ContactZhi Yinghao
Wenzhou Hospital of Traditional Chinese Medicine
Outcome results
None listed