Effectiveness and safety of high-frequency jet ventilation (HFJV) and normal frequency jet ventilation (NFJV) in CT guided percutaneous microwave ablation of tumors under general anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068119

Enrollment

Unknown

Registered

2023-02-08

Start date

2023-02-15

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary tumor

Interventions

Control group (intermittent positive pressure ventilation group):intermittent positive pressure ventilation group

Treatment group(high frequency jet ventilation and normal frequency jet ventilation group ):high frequency jet ventilation and normal frequency jet ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.For patients who plan to perform percutaneous microwave ablation of lung tumors under CT guidance under selective general anesthesia, the lung tumor to be ablated is a single lung tumor (0.5cm = the maximum diameter of the tumor = 3cm, and the minimum distance from the tumor edge to the pleura>0.5cm); Or the lung tumor to be ablated is multiple lung tumors, one of which meets the conditions of 0.5cm = maximum tumor diameter = 3cm, and the minimum distance from the tumor edge to the pleura > 0.5cm. When multiple lung tumors meet the conditions, the one with the largest tumor diameter is selected; 2.Aged 18-85; 3.American Society of Anesthesiologists (ASA) grade I-III; 4.Good compliance, voluntary participation in the test, and signed a written informed consent.

Exclusion criteria

Exclusion criteria: 1.Asthma, chronic obstructive pulmonary disease, and severe pulmonary bullae; 2.BMI>35kg/m2 ; 3.People with respiratory infectious diseases, such as tuberculosis and influenza; 4.People with serious cardiovascular and cerebrovascular diseases; 5.Those with severe airway stenosis; 6.Operation in prone position; 7.People with other contraindications to anesthesia.

Design outcomes

Primary

Measure	Time frame
Duration of microwave ablation needle insertion;depth of ablation needle insertion;	—

Secondary

Measure	Time frame
Blood gas analysis at the end of ablation needle insertion;Demographic data;pneumothorax;basic Blood gas analysis;At the end of the operation Blood gas analysis;Number of ablation needle insertion;	—

Countries

China

Contacts

Public ContactYingbin Shi

shiyingbin6@163.com15810962276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026