acute pancreatitis
Conditions
Interventions
experimental group:Conventional therapy + aspergillus oryzae pancrease tablets
Control group:Conventional therapy
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: The age range is 18 to 85 years old; Patients with moderately severe or severe acute pancreatitis meeting AP diagnostic criteria; The diagnosis of fecal elastin was mild to moderate pancreatic exocrine insufficiency Agree and sign the informed consent
Exclusion criteria
Exclusion criteria: recurrent acute pancreatitis; Other possible causes of PEI include chronic pancreatitis, celiac disease, diabetic gastroparesis, cystic fibrosis, pancreatic tumors, etc; Hyperthyroidism,; previous gastrointestinal or pancreatic surgery; gastrointestinal debut obstruction, or mechanical ileus; internal bdominal pressure above 15mmHg; Pregnant or lactating woman; Allergic to pancreatic enzymes; Refuse to sign informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nutritional intolerance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Remission rate of nutritional intolerance after 24 hours of pancreatic enzyme therapy;Defecation frequency;stool property;Abdominal pain;abdominal distension;weight;BMI;albumin;prealbumin; | — |
Countries
China
Contacts
Public Contacthewenhua
The First Affiliated Hospital of Nanchang University
Outcome results
None listed