Clinical study on the improvement of perioperative neurocognitive disorders in elderly patients undergoing gastrointestinal surgery by Tongdu Yangshen Acupuncture

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068102

Enrollment

Unknown

Registered

2023-02-07

Start date

2023-02-08

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative neurocognitive disorders

Interventions

Control group:N/A

Electric acupuncture group:Tongdu Yangshen Acupuncture

Eligibility

Sex/Gender

All

Age

65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients who plan to receive gastrointestinal tumor surgery under endotracheal intubation and general anesthesia; 2. ASA grade ?~?, surgery grade 3~4; 3. Aged 65-85 years; 4. Volunteer to participate in research projects.

Exclusion criteria

Exclusion criteria: 1. Patients with central nervous system or mental diseases; 2. Patients with cognitive dysfunction before surgery; 3. Patients whose operation time is expected to exceed 2.5 hours; 4. Long-term preoperative use of sedatives, antidepressants, NSAIDs (non-steroidal anti-inflammatory drugs) and hormones; 5. Alcoholics and drug addicts; 6. Severe disorder of internal environment and insufficiency of heart, lung, liver and kidney function; 7. Severe visual or hearing impairment or inability to communicate; 8. Those who have systematically received nootropics from Chinese and Western medicine in the past two weeks; 9. Patients who participated in other clinical trials 3 months before study inclusion; 10. Patients with known drug or liquid allergy.

Design outcomes

Primary

Measure	Time frame
Incidence of perioperative cognitive dysfunction (cognitive function score);	—

Secondary

Measure	Time frame
Incidence of hypotension during anesthesia induction;Intraoperative cerebral oxygen saturation;Intraoperative vital signs;Vascular drug dosage in operation center;Intraoperative hemodynamics;Intraoperative lactic acid value;Postoperative stay in ICU and total postoperative hospitalization;	—

Countries

China

Contacts

Public ContactDeng Jinhe

Guangdong Provincial Hospital of Chinese Medicine(The Second Affiliated Hospital of Guangzhou University of Chinese Medicine)

djh13751803925@163.com+86 137 5180 3925

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026