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Effect of SARS-COV-2 on human endometrial receptivity

Effect of SARS-COV-2 on human endometrial receptivity

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068080
Enrollment
Unknown
Registered
2023-02-06
Start date
2022-12-14
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

human endometrial receptivity

Interventions

infected with SARS-Cov-2:NA
controlled :NA

Sponsors

Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Frozen-thawed embryo transfer was/will be done after 9th November, 2022. And the cryopreservation was done before 7th December, 2022. 2. Fresh embryo transfer was done from 9th November 2022 to 7th December 2022. 3. Endometrial receptivity test was/will be done from 14th December, 2022 to 31st December,2023.

Exclusion criteria

Exclusion criteria: 1. Uterine reasons causing embryo implantation failure, such as: adenomyosis, uterine malformation, uterine cavity adhesion, scarred uterus. 2. Medical history of recurrent implantation failures. 3. Diseases negatively affecting embryo implantation, such as SLE, hypertension, diabetes mellitus, insulin resistance and anti-phospholipid syndrome.

Design outcomes

Primary

MeasureTime frame
RNA-seq of human endometrial tissue;Clinical pregnancy rate;embryo implantation rate;rate of early pregnancy loss;

Secondary

MeasureTime frame
live birth rate;birthweight;

Countries

China

Contacts

Public ContactYanping Li

Xiangya Hospital, Central South University

lisayanping@163.com+86 136 0731 7798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026