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Structural and component alterations in posttraumatic neve microenvironment and the underlying mechanism

Structural and component alterations in posttraumatic neve microenvironment and the underlying mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068077
Enrollment
Unknown
Registered
2023-02-06
Start date
2023-02-10
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peripheral nerve injury

Interventions

Diabetes amputation group:NA
Trauma amputation group:NA

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age >=18; 2. Diagnosed with limb necrosis and have to accept limb amputation; 3. Preoperative assessment of limb has confirmed the dysfunction of limb; 4. Able to read and write Mandarin Chinese. Understand and complete the questionnaire and provide informed consent.

Exclusion criteria

Exclusion criteria: 1. Non vascular limb wound infection 2. Impaired perception or pregnancy 3. Immunodeficiency; 4. Participate in other tests; 5. Inability to accept research interventions; 6. The following diseases exist, including but not limited to: Poorly controlled thyroid disease; Vibration induced neuropathy; Inflammatory arthritis, osteoarthritis; Suspected complex diseases of nervous system and skeletal muscle system; 7. Known abuse of drugs or alcohol.

Design outcomes

Primary

MeasureTime frame
single-cell sequencing;

Countries

China

Contacts

Public ContactFan Cunyi

Shanghai Sixth People's Hospital

cyfan@sjtu.edu.cn+86 189 3017 7799

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026