peri-operative new onset atrial fibrillation
Conditions
Interventions
Control:intravenous 100ml N.S. before operation
Magnesium (M):ivgtt 80mg/kg magnesium diluted to 100ml N.S.
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing anatomic pulmonary resection under general anesthesia; 2. ASA class I~III; 3. Age is over or equal to 65 years old; 4. Blood routine, liver and kidney function, blood coagulation, electrocardiogram, cardiac ultrasound, blood gas analysis have been monitored; 5. Those who signed the informed consent form were approved by the hospital ethics committee.
Exclusion criteria
Exclusion criteria: 1. Renal insufficiency; 2. Have experienced any type of arrhythmia in the past 6 months or the patient is currently taking any antiarrhythmic drugs; 3. Hypermagnesaemia (> 1.25 mmol/L); 4. Allergy to magnesium sulfate; 5. FEV1<=1L; 6. The patient had undergone thoracic surgery; 7. Bilateral lung resection; 8. For other reasons, the researchers find it unsuitable to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of peri-operative new onset atrial fibrillation; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypotension;bradycardia;hypertension;Other types of arrhythmias;blush;Postoperative respiratory depression (< 8 beats/min);Gastrointestinal reactions (bloating, constipation, nausea, vomiting);Length of stay in ICU (hours) and total length of stay (days);Patients who visited any health care facility for arrhythmia within 3 months after surgery;In-hospital mortality and all-cause mortality at 3 months after surgery; | — |
Countries
China
Contacts
Public ContactJin Shuqing
Shanghai Pulmonary Hospital
Outcome results
None listed