breast cancer
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Modified radical mastectomy for unilateral breast cancer for the first time; 2. Age >= 65 years; 3. No contraindications to anesthesia; 4. mini mental status examination (MMES) before operation >= 24. 5. Patients and their families are informed about the study and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Being allergy to the study drug; 2. Opioid dependence; 3. Abnormal coagulation function; 4. Patients with mental disorder or infection near the puncture point; 5. Used anticoagulant drugs and/or analgesic drugs in recent 3 months; 6. Combined with immune deficiency, infectious diseases, hematological diseases, venous thrombosis of lower limbs and dysfunction of important organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examinatlon;Confusion Assessment Method; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Hemodynamic index;blood glucose;Postoperative complications;Types and dosage of postoperative analgesics;Time of getting out of bed postoperatively;Time of first request for postoperative analgesia;The number and ratio of cases of general anesthesia in the nerve block group changing to laryngeal mask or tracheal intubation; | — |
Countries
China
Contacts
Yancheng No.1 People's Hospital