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The study on clinicopathological features and microRNA differential expression in progressive and non-progressive mycosis fungoides, and role of miR-181a-5p in the pathogenesis and progression of mycosis fungoides

The study on clinicopathological features and microRNA differential expression in progressive and non-progressive mycosis fungoides, and role of miR-181a-5p in the pathogenesis and progression of mycosis fungoides

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068039
Enrollment
Unknown
Registered
2023-02-03
Start date
2023-02-03
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mycosis fungoides

Interventions

progressive mycosis fungoides:none
non-progressive mycosis fungoides:none

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosed as classic MF by clinical histopathological examination; 2. Complete clinical and histopathological data and treatment records; 3. Patients should not have a history of active infection, autoimmune disease, or other tumors at the time of biopsy.

Exclusion criteria

Exclusion criteria: 1. Other clinical or histological subtypes of MF during the course of the disease; 2. The patient is in a state of immune deficiency or immunosuppression; 3. Patients with incomplete follow-up data.

Design outcomes

Primary

MeasureTime frame
Clinical Features(lesion, location,symptoms, involvement of lymph note);Histopathological features(changes of epidermis and dermis, epidermotropism, tumor cell morphology);micro RNA expression profile;

Secondary

MeasureTime frame
Laboratory examination(EOS, LDH, Superficial lymph node ultrasound);

Countries

China

Contacts

Public ContactLin Wang

West China Hospital, Sichuan University

lkzwl@126.com+86 189 8060 1701

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026