Migraine
Conditions
Interventions
the migraine without aura group:Acupuncture
the migraine without aura with abnormal facial skin pain group:Acupuncture
the chronic migraine group:Acupuncture
Sponsors
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine/ Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: a.the migraine without aura group (group A) Participants will be recruited if they: a) are between the ages of 20 and 50; b) have been diagnosed with migraine without aura according to the third edition of the International Classification of Headache Disorders (ICHD-3); c) have more than five attacks per month, predominantly unilateral or bilateral headaches, with a history of migraine without aura for over a year; d)are non-allergic and have no contraindications to acupuncture; e) have no past medical or family history of neurological disorders; f) have not used any psychiatric drugs in the past three months and no vasoactive drugs in the previous half month; g) have no fMRI contraindications or metal implants in the body. (Note: Anyone who does not meet any of the above conditions cannot be included.) b. the migraine without aura with abnormal facial skin pain group (group B) Same inclusion criteria as above a(a)-g));At the same time, h) patients experience unilateral or bilateral abnormal facial skin pain during daily activities such as combing hair, taking a shower, being exposed to a superheated or supercooled environment, etc. both during the ictal and interictal periods. (Note: Anyone who does not meet any of the above conditions cannot be included.) c.the chronic migraine group (group C) Participants will be recruited if they: a) are between the ages of 20 and 50; b) have been diagnosed with chronic migraine according to the third edition of the International Classification of Headache Disorders (ICHD-3); c) have more than five attacks per month, predominantly unilateral or bilateral headaches, with a history of chronic migraine for over a year; d) have unilateral or bilateral abnormal facial pain in daily life, such as combing hair, taking a shower, being exposed to a superheating and supercooling environment, etc., both during the ictal and interictal periods; e) are non-allergic and have no contraindications to acupuncture; f) have no past medical or family history of neurological disorders; g) have not used any psychiatric drugs in the past three months and no vasoactive drugs in the previous half month; h) have no fMRI contraindications or metal implants in the body. (Note: Anyone who does not meet any of the above conditions cannot be included.)
Exclusion criteria
Exclusion criteria: a.the migraine without aura group (A group) Participants will be excluded if they: a) have secondary migraine symptoms, such as a headache caused by hypertension, cerebral hemorrhage, cerebral infarction, and organic lesions in the brain; b) are combined with severe primary disorders like those of the blood, nervous, endocrine, digestive, urinary, and respiratory systems; c)have particular types of migraine, such as ophthalmoplegic migraine, hemiplegic migraine, and others; d) are prone to co-infection and tend to bleed; e) are carrying a pregnancy, ready to be pregnant, or lactating mothers; f) have mental disorders or other reasons at prevent them from cooperating with the examination, therapy, and follow-up. (Note: patients who meet the above conditions are excluded.) b.the migraine without aura with abnormal facial skin pain group (B group) Same exclusion criteria as above a)—f) c.the chronic migraine group (C group) Same exclusion criteria as above a)—f)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the Hot Pain Thresholds;the Data analysis values for Brain fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Mechanical Pain Threshold;the Visual Analogue Scale;the Headache Impact Test ;the MOS 36- Item Short Form Health Survey;the Headache Diary; | — |
Countries
China
Contacts
Public ContactLan Lei
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine/ Chengdu University of Traditional Chinese Medicine
Outcome results
None listed