Intestinal atresia or stenosis, intestinal duplication malformation, intestinal perforation, etc.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. children 0-6 months of age undergoing intestinal anastomosis (e.g. intestinal atresia or stricture, intestinal duplication malformation, intestinal perforation, etc.) 2. enteral nutritional support can be started within 48h after the operation. 3. the enteral nutrition preparation can be either amino acid-based enteral nutrition powder or whole protein-based enteral nutrition preparation 4. the child's parents or legal guardians (aged >=18 years) voluntarily sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. premature babies (<37 weeks of gestational age at birth) 2. very low birth weight children (<1500g). 3. children with other complications leading to gastrointestinal symptoms. 4. exclusively breastfed children. 5. children with contraindications to enteral nutrition (e.g. intestinal obstruction, severe shock, intestinal ischaemia, high-energy intestinal fistula, severe gastrointestinal bleeding, etc.). 6. children who have participated in other clinical studies within the last 3 months. 7. Other conditions that the investigator determines to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative feeding intolerance in both groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Indicator of recovery of gastrointestinal function: time to full enteral nutrition;Changes in nutritional status;Length of stay in hospital;Anthropometric indicators: length, weight head circumference growth rate;Nutrition Risk Screening Score;Observed indicators of compliance; | — |
Countries
Chian
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology