Dysthyroid optic neuropathy
Conditions
Interventions
experimental group:taurine
control group:placebo
healthy control group:none
Sponsors
Eye Hospital Affiliated to Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 40-60 years; 2. Right-handed; 3. Education>= 5 years; 4. in good physical condition and able to walk around or with assistance, able to complete the visual and visual test; 5. After fully understanding the safety of the research project, be willing to actively cooperate with the research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients have eye diseases that may affect visual function, such as corneal ulcers, cataracts, retinal vascular diseases, retinal detachment and other optic nerve diseases, etc; 2. History of other eye surgery, orbital wall decompression surgery and ocular radiation therapy ; 3. Patients with acute TAO and patients with eyelid insufficiency ; 4. History of diabetes and hypertensive lesions; 5. History of brain tumor, brain trauma or cerebrovascular disease; 6. Have a history or family history of neurological or psychiatric diseases; 7. There are poorly controlled diabetes mellitus or serious heart, liver, kidney dysfunction and other major systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Taurine;ß-alanine;quick Contrast sensitivity function;visual field; | — |
Secondary
| Measure | Time frame |
|---|---|
| L-Carnosine;L-histidine;Superoxide Dismutase;Malonic dialdehyde;Intestinal flora community structure and quantitative detection; | — |
Countries
China
Contacts
Public ContactYunhai Tu
Eye Hospital Affiliated to Wenzhou Medical University
Outcome results
None listed