herpes zoster
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Signed the informed consent form and was willing to participate in the study; 2. For those aged 50 years and above, gender is not limited; 3. HZ was diagnosed in thoracic segment (T2 - 10); 4. The eruption occurred within 1~7 days; 5. Baseline pain intensity 11-point NRS score = 4 points (baseline pain intensity is the average pain intensity score within 24 hours before randomization); 6. Patients without antiviral and analgesic treatment
Exclusion criteria
Exclusion criteria: 1. HZ in other parts than thoracic segment; 2. Patients with severe diabetes mellitus, malignant tumor, severe cardiovascular and cerebrovascular diseases, liver, kidney, hematopoietic system and other primary diseases or systemic failure, mental patients, hemophilia patients, patients with bleeding tendency and local skin lesions ulceration and infection; 3. Pregnant or lactating women; 4. The patient is in critical condition, and it is difficult to make exact evaluation on the effectiveness and safety of treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain grade;Incidence of PHN; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin lesion recovery;Quality of life assessment;Peripheral blood inflammatory mediators;Transcriptomics of Peripheral Blood Mononuclear Cells; | — |
Countries
China
Contacts
The First People's Hospital of Changde City