Polycystic Ovary Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.The diagnostic criteria for both PCOS and insulin resistance were met; 2. Between 20 and 40 years old; 3. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclude hyperandrogenemia caused by other causes, such as Cushing syndrome, delayed congenital adrenal hyperplasia, androgen-secreting ovarian and adrenal tumors, and other diseases leading to ovulation dysfunction, such as pituitary or hypothalamic amenorrhea, hyperprolactinemia, premature ovarian failure, etc.; 2. diabetes, thyroid dysfunction and other endocrine diseases, autoimmune diseases, malignant tumors; 3. Received PCOS-related treatment within 3 months, including short-acting contraceptives, anti-androgens, ovulation promoting drugs or ovarian perforation surgery; 4. Pregnancy or lactation period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of sex hormones and related indexes of glucose and lipid metabolism;pregnancy rate, abortion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicle development was monitored by ultrasound;Detection of ß-endorphin, gonadotropin releasing hormone and insulin signaling factor; | — |
Countries
China
Contacts
Fujian Provincial Maternal and Child Health Hospital