Regional versus systemic dexmedetomidine as an adjuvant to lidocaine for intravenous regional anesthesia in healthy volunteers: A randomized crossover study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067978

Enrollment

Unknown

Registered

2023-02-02

Start date

2023-02-03

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group AB:Subjects received systemic 0.5 µg/kg dexmedetomidine 20 mL via right-hand and 0.5% lidocaine 25 mL for left forearm IVRA. After a two-week wash period, they received systemic saline 20 mL via

Group BA:Subjects received systemic saline 20 mL via right-hand and 0.5 µg/kg dexmedetomidine plus 0.5% lidocaine 25 mL for left forearm IVRA. After a two-week wash period, they received systemic 0.5

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers aged 18-45 years, with the American Association of Anesthesiologists (ASA) classification?.

Exclusion criteria

Exclusion criteria: 1. known allergy or hypersensitivity to the study medications (lidocaine or dexmedetomidine) 2. pregnancy, physiological, or lactation period 3. history of medication or alcohol abuse 4. BMI >= 30 kg/m2 5. Inability to understand or adhere to the study protocol

Design outcomes

Primary

Measure	Time frame
Tourniquet tolerance time;	—

Secondary

Measure	Time frame
Onset time of sensory block;Recovery time of sensory block;	—

Countries

China

Contacts

Public ContactYusheng Yao

Fujian Provincial Hospital

fjslyys@126.com+86 13559939629

Outcome results