Intestinal cancer
Conditions
Interventions
R:PEEP=0
F:PEEP=5
P:Individualized PEEP
Sponsors
Department of Anesthesiology, Chaohu Hospital Affiliated to Anhui Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. It meets the diagnostic criteria for colorectal cancer and has indications for laparoscopic surgery 2. Complete clinical data, age>65, BMI<35Kg/m 2 3. American Society of Anesthesiologists Grade ? - ? 4. The patient himself agrees and signs the study consent form
Exclusion criteria
Exclusion criteria: 1. Pulmonary infection, pulmonary abscess, COPD, asthma, pulmonary hypertension and other respiratory diseases existed within 1 month before operation 2. Previous patients with diaphragm paralysis, cervical spinal cord injury, sepsis, neuromuscular junction disease and external diaphragm pacemaker treatment 3. Thoracic trauma, severe cardiac and renal dysfunction 4. Combined with other malignant tumors, connective tissue diseases, immune system diseases and other systemic chronic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm mobility;End expiratory diaphragm thickness;Diaphragm thickness at the end of inspiration;Change rate of diaphragm thickness;Postoperative diaphragmatic dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation indexes, including tidal volume (mL), PEEP (cmH2O), airway plateau pressure (cmH2O), airway peak pressure (cmH2O), and mechanical ventilation time;The hemodynamic indicators included heart rate and arterial pressure; | — |
Countries
China
Contacts
Public ContactXia Xiaoqiong
Department of Anesthesiology, Chaohu Hospital Affiliated to Anhui Medical University
Outcome results
None listed