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Effect of dexmedetomidine combined with nalbuphine anesthesia on relieving heart rate and blood pressure increase in pediatric bronchoalveolar lavage

Application of dexmedetomidine combined with nalbuphine in pediatric bronchoalveolar lavage anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067972
Enrollment
Unknown
Registered
2023-02-01
Start date
2023-02-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial lung infection or atelectasis and other pulmonary diseases in children

Interventions

D:Dexmedetomidine was injected intravenously before surgery
N:Nabulphine was given intravenously before surgery
DN:Before surgery, dexmedetomidine and nalbuphine were injected intravenously

Sponsors

Liaocheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children who planned to undergo bronchoalveolar lavage in Liaocheng People's Hospital from January 2023 to June 2025;Age: 1~12 years old, ASA grade I ~III; Agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: Children with severe organic diseases; Children with preoperative tracheal intubation; Children with abnormal coagulation; Children with liver and kidney insufficiency; Children with a history of opioid abuse; Children with mental illness; Children with history of diabetes and hypertension

Design outcomes

Primary

MeasureTime frame
Intraoperative propofol dosage;

Secondary

MeasureTime frame
Heart rate, blood pressure and pulse oxygen saturation at each time point;Minimum pulse oxygen saturation from the time of pumping to the time of wakefulness;The number of episodes of hypoxemia between pumping and wakefulness;The number of body movements of the child during the operation;Bis value at each time point;

Countries

China

Contacts

Public ContactLiu Zunyuan

Liaocheng People's Hospital

ly29.love@163.com+86 18263511977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026