residual cough after post-acute swquelae of COVID-19
Conditions
Interventions
control group:Oral methoxamine capsules
Sponsors
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Positive nucleic acid or antigen test of COVID-19 2. Cough from the onset of the disease, lingering, irritating dry cough, or accompanied by a small amount of white phlegm, the duration of 4-8 weeks 3. Visual analog scale (VAS) of cough severity >= 4 points 4. Lung CT examination showed no obvious abnormality or thickening of lung texture 5. Exclude cough caused by other causes 6. Age range from 18 to 65 years old 7. Informed consent, and voluntarily sign the informed consent
Exclusion criteria
Exclusion criteria: 1. Body temperature (axillary temperature) >= 37.0?; 2. Patients who had taken codeine, dextromethorphan, compound methoxamine capsules and other antitussive drugs within 24 hours before inclusion; 3. cough caused by chronic obstructive pulmonary disease, acute onset of chronic bronchitis, tuberculosis and other diseases; 4. complicated with serious primary diseases of cardiovascular and cerebrovascular systems, liver, kidney and hematopoietic systems and other organic diseases such as tumors; 5. Those who have language or hearing impairment, intellectual impairment, serious mental illness and other conditions that cannot cooperate; 6. Pregnant and lactating women and those who have fertility requirements in the past six months; 7. Allergic to the study drug; 8. Participants in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of VAS for cough severity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Leicester Cough Questionnaire;Cough hypersensitivity questionnaire;Proportion of patients with VAS reduction =3 points;Cough remission and resolution time; | — |
Countries
China
Contacts
Public ContactDai Qiufu
Department of Acupuncture and moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Outcome results
None listed