Hysteromyoma
Conditions
Interventions
Group 1:Lidocaine 1.5mg/kg, ketamine 0.25mg/kg
Group 2:sufentanil 0.3ug/kg
Sponsors
Yichang Central People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-50 years old; 2. ASA grade I-II; 3. Estimated anesthesia operation time <= 240 min; 4. The patient himself or the legally authorized person signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI): BMI >= 30 kg/m2 or upper limit of normal value); liver function impairment (ALT and or AST > 1.5 times upper limit of normal value); 10. Abnormal breath-hold test; 11. Patients with a history of severe head trauma and intracranial hypertension within 6 months; 12. Patients with mental or neurological diseases, or patients who cannot express their wishes correctly; 13. Patients with a history of taking sedative and analgesic drugs or monoamine oxidase inhibitors for a long time; 14. Expected surgical blood loss is greater than 100 mL; 15. Those who have participated in other drug clinical trials in the past month; 16. Patients who cannot perform ASA or FLACC scoring due to various reasons; 17. With other conditions, the investigator believes that the patients are not suitable for inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative sore throat score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time;Waking hours;Degree of sedation;Hemodynamic changes after intubation;Number of cases using m-hydroxylamine;Number of atropine use cases;Number of postoperative nausea and vomiting cases;Time to recovery of bowel function;Quality of postoperative recovery; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People's Hospital
Outcome results
None listed