novel coronavirus-infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age of 18-85 years old; 2. receiving cardiac surgery under CPB or ECMO support; 3. SARS-CoV-2 nucleic acid positive nasopharyngeal or oropharyngeal swabs within 72 hours before receiving CPB or ECMO; 4. Informed consent was signed.
Exclusion criteria
Exclusion criteria: 1. participated in other intervention studies within 1 month and had a great impact on this study; 2. Allergic to CPB or ECMO circuits; 3. expected survival time less than 24 hours; 4. patients with other conditions deemed by the investigators to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heparin resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Routine coagulation monitoring;heparin monitor;anticoagulation protein;anticoagulation factors;endothelial function;inflammatory factors;lymphocyte subpopulation;autoimmunity;NETS;The oxygenator exports the nucleic acid of SARS-CoV-2; | — |
Countries
China
Contacts
Fuwai Hospital, CAMS&PUMC