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Evaluation of the effectiveness and safety of prone ventilation in severe and critically ill patients with COVID-19 by three-person

Evaluation of the effectiveness and safety of prone ventilation in severe and critically ill patients with COVID-19 using the three-person

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067934
Enrollment
Unknown
Registered
2023-01-31
Start date
2023-01-22
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Sponsors

Qilu Hospital of Shandong University Dezhou Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have been tested positive for nucleic acid or antigen or for isolation and culture of the novel coronavirus, and confirmed by chest CT, meet the diagnostic criteria for novel coronavirus pneumonia and meet the diagnosis and treatment protocol for novel coronavirus infection (trial version 10) for severe and critically ill patients. 2. Patients diagnosed with prone ventilation; 3. Mechanical ventilation >= 24h; 4. Patients or family members were informed and agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Coma, increased intracranial pressure, subarachnoid hemorrhage, arrhythmia, irreversible organ function injury; 2. Asthma, the presence of severe life-threatening hypoxemia, severe obesity, acute bleeding, spinal injury, sternal and pelvic fractures; 3. Recent abdominal surgery; Combined with hemodynamic instability; 4. other patients who cannot tolerate face-down posture.

Design outcomes

Primary

MeasureTime frame
Oxygenation Index;

Secondary

MeasureTime frame
Heart Rate;Mean Arterial Pressure;Central Venous Pressure;Mean airway pressure;Tidal Volume;Oxygen Partial Pressure;Edema of the face;Occurrence of stress injury;Catheter anomaly;Reflux and aspiration of gastric contents;Average time consuming;Length of ICU Stay;Duration of tracheal intubation;

Countries

China

Contacts

Public ContactZhang Binbin

Qilu Hospital of Shandong University

zhangbinbinql@163.com+86 18560085288

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026