Effects of human umbilical cord blood mononuclear cells on the repair of thin endometrium

Clinical study on the treatment of thin endometrium with umbilical cord blood mononuclear cells

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067923

Enrollment

Unknown

Registered

2023-01-31

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thin endometrium

Interventions

Drug control group:Estrogen and progesterone therapy

cord blood mononuclear cell therapy group:Umbilical cord blood mononuclear cells and estrogen and progesterone therapy

Placebo control group:None

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age < 45 years old; 2. Endometrial <= 0.7cm indicated by vaginal ultrasound during ovulation; 3. Intrauterine adhesions; 4. Secondary infertility due to thin endometrium, patients with frozen embryo transfer cycle cancellation, Patients with repeated embryo transfer failures; 5. patients signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Various serious chronic systemic diseases; 2. Liver and kidney dysfunction; 3. Patients with chromosomal abnormalities; 4. Congenital uterine malformation; 5. Severe adenomyosis; 6. Pregnancy contraindications; 7. Arteriovenous History of thrombosis; 8. History of hormone-dependent malignant tumors; 9. Patients with history of pelvic radiotherapy; 10. Patients who cannot cooperate with the study.

Design outcomes

Primary

Measure	Time frame
Endometrium;Intimal blood flow;	—

Secondary

Measure	Time frame
Embryo implantation rate;Pregnancy rate;Cycle cancellation rate;	—

Countries

China

Contacts

Public ContactHong Li

QiLu Hospital of ShanDong University DeZhou Hospital

didayu@126.com+86 13869232719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026