labor induction of term pregnancy
Conditions
Interventions
artificial rupture of membrane:artificial rupture of membrane
induced of labor with misoprostol:misoprostol 25 ug was placed vaginally for cervical ripening
Sponsors
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Term pregnancy, singleton head presentation, aged 18-40 years (not inclucing 18 and 40), and no contraindication for vaginal delivery; 2. Bishop score < 6 after Foley catheter balloon cervical induction; 3. Understanding and signing informed consent.
Exclusion criteria
Exclusion criteria: 1. Premature rupture of membranes, inflammation of the reproductive system, contraindication of balloon or misoprostol for ripening, carriage of group B Streptococcus, pelvic abnormalities; 2. History of previous uterine surgery; 3. Severe fetal malformations, fetal distress, Stillbirth, severe fetal growth restriction (estimated fetal weight < 3%),placental margin less than 6 cm from the cervix; 4. Asthma, glaucoma, allergy to prostaglandin preparations; 5. Use of other methods of cervical maturation; 6. Cognitive or intellectual disability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from intervention to delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cesarean section indication;Cesarean section rate;Indications for operative vaginal birth;Operative vaginal birth rate;Time from intervention to vaginal delivery;time from intervention to active phase;rate of labor analgesia;rate of oxytocin using;Rate of vaginal delivery at 24 hours;Rate of vaginal delivery at 48 hours; | — |
Countries
China
Contacts
Public ContactYimin Dai
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital
Outcome results
None listed