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Exploration of clinical characteristics and risk factors in patients with immune checkpoint inhibitor-associated myocarditis

Exploration of clinical characteristics and risk factors in patients with immune checkpoint inhibitor-associated myocarditis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067898
Enrollment
Unknown
Registered
2023-01-31
Start date
2023-01-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

immune checkpoint inhibitor-associated myocarditis

Interventions

Case series:Not applicable

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The included population was patients with malignant tumors with complete clinical data who received immunotherapy and were diagnosed with ICIS related myocarditis between January 2021 and September 2022 at the First Affiliated Hospital of Zhengzhou University; 2. Diagnosis of myocarditis following the diagnostic criteria for myocarditis proposed by bonaca et al: (1) Histopathological features on endomyocardial biopsy or autopsy suggestive of myocarditis; (2) Diagnosis of myocarditis by cardiac magnetic resonance imaging in conjunction with clinical presentation of myocarditis and elevated biomarkers or electrocardiographic evidence; 3. Echocardiography showed new onset wall motion abnormalities along with clinical manifestations of myocarditis, elevated biomarkers, electrocardiographic evidence, and negative coronary angiography.

Exclusion criteria

Exclusion criteria: Patients who did not use ICI by course were excluded.

Design outcomes

Primary

MeasureTime frame
All-cause mortality;

Secondary

MeasureTime frame
Cardiovascular adverse events;

Countries

China

Contacts

Public ContactDeliang Shen

The First Affiliated Hospital of Zhengzhou University

dlshen@zzu.edu.cn+86 15993376385

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026