Hypotension
Conditions
Interventions
Group N1:norepinephrine 3 ug
Group N2:norepinephrine 4 ug
Group N3:norepinephrine 5 ug
Group N4:norepinephrine 6 ug
Group N5:norepinephrine 7 ug
Sponsors
Women's Hospital School of Medicine Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Single fetus PE patients who plan to perform elective cesarean section and choose combined spinal epidural anesthesia; 2. ASA grade II-III; 3. Aged 18-40 years; 4. Obtain ethical permission and informed consent of patients before the experiment; 5. The diagnostic criteria of preeclampsia are: blood pressure >= 140/90 mmhg, measurement interval at least 4 hours, 24-hour proteinuria >= 300 mg or test paper proteinuria >= 1+.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic hypertension, diabetes and serious cardiovascular and cerebrovascular diseases; 2. Patients with known fetal abnormalities or intrauterine growth restriction; 3. Patients with obstetric complications include premature rupture of membranes, placenta previa and placental abruption; 4. Those who have contraindications to intraspinal anesthesia or research related drugs; 5. The height is too high or too low (> 180 cm or < 150 cm); 6. Gestational age < 28 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;weight;height;Anesthesia induction-delivery time;Uterine incision-delivery time; | — |
Countries
China
Contacts
Public ContactFeng Fu
Women's Hospital School of Medicine Zhejiang University
Outcome results
None listed