Parkinson's disease
Conditions
Interventions
TCM Group:Dialectical Chinese medicine decoction
control group:Blank
Sponsors
Beijing Rehabilitation Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as idiopathic PD according to the 2015 MDS criteria; 2. Diagnosed as constipation according to Rome III diagnostic criteria; 3. Aged 30-80 years; 4. Hoehn and Yahr classification 1-4; 5. Sign informed consent and be able to insist on completing the entire treatment process.
Exclusion criteria
Exclusion criteria: 1. Patients who do not take medication under the guidance of a professional doctor or cannot take medication regularly; 2. Patients with intestinal organic lesions such as intestinal polyps, intestinal tuberculosis, Crohn's disease, tumors and ulcers. etc.; 3. Secondary constipation caused by uremia, muscular dystrophy, multiple sclerosis, hypothyroidism and other system diseases; 4. Patients with severe heart, brain, liver, kidney, blood system diseases, as well as mental disorders or dementia; 5. Higher serum creatinine, ALT or AST than twice the normal value; 6. According to the judgment of the researcher, patients who are unable to cooperate throughout the research due to drug abuse or poor adherence; 7. Participated in other studies in the past 2 weeks or is currently participating in other clinical trials; or has taken other traditional Chinese medicine preparations in the past 3 months; 8. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| constipation severity instrument; | — |
Secondary
| Measure | Time frame |
|---|---|
| Movement Disorder Society Unified-Parkinson Disease Rating Scale, MDS-UPDRS;NMSS, non-motor symptom scale;Parkinson's disease sleep scale, PDSS;PDFS, Parkinson's disease fatigue scale; | — |
Countries
China
Contacts
Public ContactZhaohui Jin
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Outcome results
None listed