moyamoya disease
Conditions
Interventions
Gold Standard:Functional comprehensive assessment
Index test:contrast-enhanced ultrasound, ultrafast ultrasound
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Normal cerebral blood perfusion: 1. Aged 18-80 years, gender unlimited; 2. Understand and sign the informed consent; 3. Non-dural tumor lesions (such as meningioma) requiring craniotomy and non-cerebrovascular disease patients were examined. Moyamoya disease: 1. Aged 18-80 years, gender unlimited; 2. Understand and sign the informed consent; 3. Patients with moyamoya disease requiring craniotomy after examination.
Exclusion criteria
Exclusion criteria: 1. Patients with severe arrhythmia; 2. Patients with respiratory failure requiring ventilator use; 3. Patients with heart disease with right-to-left shunt, patients with known severe pulmonary hypertension (pulmonary pressure > 90 mmHg), uncontrolled essential hypertension, and patients with adult respiratory distress syndrome; 4. Patients with unstable cardiovascular function whose dobutamine use is contraindicated; 5. Patients with anaphylaxis after receiving SonoVue (contrast agent) injection; 6. Patients with myocardial infarction and myocardial ischemia; 7. Patients with known pregnancies; 8. Participants in other clinical trials during the same period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| contrast-enhanced ultrasound;ultrafast ultrasound;functional comprehensive assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| CE MRI; | — |
Countries
China
Contacts
Public ContactHong Ding
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed