coronary artery disease
Conditions
Interventions
Experimental:colchicine 0.5 mg qd
Control group:No
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-85 years; 2. Patients with ACS or CCS undergoing IVUS-guided coronary intervention, and angiography showed at least one lesion with 50-70% stenosis proximal to the PCI vessel or non-PCI vessel in addition to the culprit lesion; 3. Patients who agree to be enrolled in the trial providing signed written informed consent
Exclusion criteria
Exclusion criteria: 1. Glomerular filtration rate 3 times the upper limit of normal); 3. Patients with hematological tumors or abnormalities of the blood routine examination (hemoglobin < 100 g/L, platelet count < 100 x 10^9/L, white blood cell count < 3.5 x 10^9/L); 4. Patients who have received colchicine for other indications or who have had an adverse reaction to colchicine; 5. Hemodynamic instability or heart failure with NYHA Class III-IV; 6. History of coronary artery bypass surgery; 7. Valvular heart disease considered likely to require intervention; 8. Patients with Gout.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percent atheroma volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| total atheroma volume; | — |
Countries
China
Contacts
Public ContactPeiren Shan
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed