glaucoma
Conditions
Interventions
experimental group:press-needle
placebo group:Comfort needle
Sponsors
Mianyang Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with primary open-angle glaucoma (POAG): Open anterior chamber angle, pathologic high intraocular pressure (HIOP) [24 h peak IOP > 21 mmHg (1 mmHg = 0.133 kPa)], characteristic glaucomatous neuropathy (retinal nerve fiber layer defect, RNFLD or optic disc chang), and/or visual field loss, exclusion of other causes result in HIOP, only one eye from each patient will be chosen; 2. Have a visual field defect that could be evaluated by standard automated perimetry (reliability factor = 0.3; 6. Aged 18-75 years; 7. Be in a conscious status and able to cooperate with the examination and treatment; 8. Be willing to take part in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Poorly controlled IOP ( 18 mmHg) accompanied by thin filtering cystic bleb or bleb leakage; 2. Other macular degeneration, cataract, proliferative diabetic retinopathy and retinal vascular occlusion or other diseases might cause visual field loss; 3. People who take other medications and other treatments during treatmentpregnancy or lactation; 4. Pregnant or lactating patients; 5. Abnormal severe primary hepatic or renal or serious systemic diseases such as heart diseases, primary hypertension, diabetes mellitus, or gastric ulcer; 6. An allergic history to the ingredients of Press-needle or mecobalamin tablets; 7. Poor treatment compliance, unable to follow up regularly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean change in best corrected visual acuity (BCVA);Visual field detection;Optical Coherence Tomography Angiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraocular pressure;color Doppler flow imaging;Change in the number of patients with different grades of TCM symptoms; | — |
Countries
China
Contacts
Public ContactHongji Liu
Mianyang Central Hospital
Outcome results
None listed