Attention deficit hyperacitivity disorder
Conditions
Interventions
TCM treatment group:Jingling Oral Liquid for 3 months
Western medicine treatment group:Tromoxetine hydrochloride for 3 months
Sponsors
Sun Yat-sen Memorial Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: (This study can be considered if all the following conditions are met) 1. Inpatients or outpatients who meet the diagnostic criteria for ADHD in DSM-5; 2. Aged 6-12 years, regardless of gender, weight >= 20 kg; 3. RS lV Parent: Inv score for boys is not less than 25 points, and for girls is not less than 22 points, or the score of the subtype diagnosed in the first and second interviews is greater than 12 points; In addition, in the first and second interviews, CGI-S scores >= 4; Normal IQ (WIS score >= 75); 4. The legal guardian shall sign the informed consent before the test; Subjects aged 8 and above should also sign the children's informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have more serious heart, liver, kidney, glaucoma, prostate hypertrophy and other medical diseases; Or have epilepsy, mental retardation and other neuropsychiatric diseases; 2. The diagnosis was tic disorder; 3. The researcher thinks that the auxiliary examination and laboratory examination are abnormal with clinical significance; 4. Participated in clinical trials of other drugs within 3 months before enrollment; 5. Allergic to some component in Jingling Oral Liquid; 6. Monoamine oxidase inhibitors (MAOI), antipsychotics, antidepressants and mood stabilizers were used 2 weeks before enrollment; 7. Suffer from somatic diseases that can significantly enhance sympathetic system activity (such as catecholamine secreting neuroma), or take sympathomimetic drugs (such as salbutamol, inhaled aerosol, pseudopilocarpine) every day; 8. The researchers believe that other common diseases or drugs being taken may interfere with the safe use of Jingling Oral Liquid; 9. At any stage of the study, it is necessary to take psychotropic drugs other than the experimental drugs, including health care products that the researchers believe have central nervous system activity (such as melatonin (brain platinum)); 10. Suspected or confirmed history of alcohol and drug abuse; 11. A woman who is clearly or suspected of being pregnant; 12. The researcher believes that the subject and/or the parent or guardian of the subject cannot fully understand the study or comply with the requirements of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total score of RS-w-parent: inv scale for attention deficit-hyperactivity disorder (ADHD) in children and its changes before and after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| The scores and changes of Children's ADHD RS-IV-Parent: Inv scale, attention deficit subscale, hyperactivity impulse subscale.;The scores and changes of Conners' Parent Rating Scale-Short Form (CPRS-R);The scores and changes of Clinical Global Impression Scale (CGI-S) and Clinical Global Impression Improvement (CGI-I); | — |
Countries
China
Contacts
Public ContactXiangyang Luo
Sun Yat-sen Memorial Hospital Sun Yat-sen University
Outcome results
None listed