Ovarian Cancer
Conditions
Interventions
Group1:Bifidobacterium longum
Sponsors
The Second People's Hospital of Jingdezhen
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Ovarian cancer patients with PLT count greater than 300 x 10^9/L; 2. Epithelial ovarian cancer (serous adenocarcinoma, mucous adenocarcinoma, endometrioid adenocarcinoma, etc.) was confirmed by puncture pathology or highly suspected ovarian cancer was confirmed by postoperative pathology; 3. The patient was generally in good condition, aged 18-75 years, and did not have serious heart, lung, kidney, liver dysfunction or metabolic diseases.; 4. 6 courses of TC chemotherapy were received after surgery; Fresh, meso-posterior, and internal fecal samples of 10 g were collected and quickly stored at -80 degree C. Fecal DNA extraction and 16S rRNA gene sequencing were performed for intestinal flora detection; 5. No antibiotics or other drugs were used in the first 3 months after the completion of treatment.
Exclusion criteria
Exclusion criteria: 1. Have hemophilia or abnormal diseases related to the blood system; 2. Other immune diseases that cause PLT abnormality; 3. With other cancers; 4. Other chronic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| platelets;Fecal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| CA125;HE4;Coagulation function; | — |
Countries
China
Contacts
Public ContactXiaohui Wang
The Second People's Hospital of Jingdezhen
Outcome results
None listed