Effects of preoperative anxiety on physiological indexes, drug dosage during the operation and postoperative recovery of breast cancer patients under general anesthesia

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300067837

Enrollment

Unknown

Registered

2023-01-29

Start date

2022-03-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preoperative anxiety

Interventions

Stage 1: Case series:No

Stage 2: exposed group:No

Stage 2: non-exposed group:No

Eligibility

Sex/Gender

Female

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Female, Aged 18-70 years; 2. Diagnosis of breast tumor (malignancy possible) requiring surgical treatment; 3. ASA grade I-II; 4. 0-2 points assessed by Eastern Cooperative Oncology Group (ECOG); 5. Planned surgery of breast cancer including: unilateral modified radical mastectomy, unilateral modified radical mastectomy with axillary sentinel lymph node biopsy but without lymph node dissection, unilateral breast-conserving mastectomy, unilateral breast-conserving modified radical mastectomy with axillary sentinel lymph node biopsy but without lymph node dissection; 6. Good communication and written understanding and writing skills; 7. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated with severe cerebral infarction, cerebral hemorrhage, history of brain surgery, brain tumor, Parkinson's disease, Alzheimer's disease and other serious brain diseases; 2. Severe cardiovascular diseases complicated with unstable angina pectoris, myocardial infarction, severe arrhythmia, cardiac function >= III, and hemodynamic instability; 3. With mental illness or cognitive impairment, the MMSE score was illiterate <= 17 points, primary school <= 20 points, middle school or above <= 24 points; 4. Taking psychotropic drugs; 5. Pregnant or lactating women; 6. Patients undergoing other operations simultaneously; 7. Unable to cooperate with the tester.

Design outcomes

Primary

Measure	Time frame
preoperative anxiety score;Quality of Recovery-40 questionnaire;	—

Secondary

Measure	Time frame
Propofol and remifentanil dosage;Blood pressure;heart rate;blood glucose;body temperature;pain score;Nausea and vomiting score;anesthesia satisfaction score;Postoperative delirium score;age;height;weight;temperament type;education background;income level;type of health insurance;The most concerned problem in perioperative period;present illness;past history;history of medications;personal history;laboratory and aided examination;	—

Measure

Time frame

Propofol and remifentanil dosage;Blood pressure;heart rate;blood glucose;body temperature;pain score;Nausea and vomiting score;anesthesia satisfaction score;Postoperative delirium score;age;height;weight;temperament type;education background;income level;type of health insurance;The most concerned problem in perioperative period;present illness;past history;history of medications;personal history;laboratory and aided examination;

—

Countries

China

Contacts

Public ContactZhang Jian

Harbin Medical University Cancer Hospital

zhangjianwangxin@126.com+86 18045101242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026