Small cell lung cancer
Conditions
Interventions
treatment group:Online adaptive radiotherapy
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Small cell carcinoma confirmed by histology or cytology; 2. Aged 18-75 years, KPS score >= 70; 3. Limited stage; excluded malignant pleural effusion confirmed by cytology or clinical judgment, and the pleural effusion on chest CT was less than 1cm thick (no intrapulmonary metastasis at the IA-IIIC stage in the 8th AJCC stage in 2017); 4. Have measurable lesions that meet RECIST v1.1 criteria for evaluation; 5. EP/EC chemotherapy = 1 L; 7. Blood routine: neutrophil count >= 1.5 x 10^9/L, hemoglobin >= 100 g/L, platelet count >=100 x 10^9/L; 8. Renal function: serum creatinine <= 1.5 times the upper limit of normal; 9. Liver function: AST and ALT <= 2.5 times the upper limit of normal, bilirubin <= 1.5 times the upper limit of normal; 10. Fully understand the study, able to complete treatment and follow-up, and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Other malignant tumors within 5 years, excluding non-melanoma skin cancer and carcinoma in situ; 2. Uncontrolled heart disease or myocardial infarction within last 6 months; 3. Uncontrolled diabetes and hypertension; 4. Interstitial pneumonia or active pulmonary fibrosis; 5. Active infection; 6. Patients with a history of mental illness; 7. Pregnant and lactating patients; 8. Other conditions that the investigator believes not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patterns of treatment failure;Progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Incidence and severity of adverse events; | — |
Countries
China
Contacts
Public ContactMing Chen
Sun Yat-sen University Cancer Center
Outcome results
None listed