Endometrial disease
Conditions
Interventions
Group 1:Remimazolam 0 mg/kg
Group 2:Remimazolam 0.5 mg/kg
Group 3:Remimazolam 1.0 mg/kg
Group 4:Remimazolam 1.5 mg/kg
Group 5:Remimazolam 2.0 mg/kg
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing hysteroscopic surgery under intravenous anesthesia; 2. ASA grade I-II, aged 18-55 years, BMI 18-24 kg/m2; 3. No electrolyte disorder, infection, immune and endocrine system diseases, no recent use of cardiovascular drugs, non-steroidal anti-inflammatory drugs, hormone drugs and anti-psychotic drugs.
Exclusion criteria
Exclusion criteria: 1. Previous history of vaginal birth; 2. Abnormal liver and kidney function; 3. History of cardiopulmonary diseases; 4. Sleep apnea syndrome; 5. Long-term use of drugs such as diazepam; 6. Long-term users of opioids; 7. People allergic to remimazolam.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| propofol effective concentration 50 (EC50); | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative vital signs;The recovery time;Adverse reactions; | — |
Countries
China
Contacts
Public ContactXinzhong Chen
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed