Anesthesia for gastrointestinal tumor surgery
Conditions
Interventions
H Group:Clinical application of maintenance of cyclophosphol anesthesia
B Group:Clinical application of maintenance of prophol anesthesia
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 60-80 years; 2. ASA grade I-III; 3. BMI 20-30 kg/m2; 4. All were diagnosed as gastric tumor, colon tumor and rectal tumor by clinical diagnosis, imaging and pathological examination; 5. No relevant drug allergy history.
Exclusion criteria
Exclusion criteria: 1. History of mental and nervous system diseases (such as cerebrovascular disease, epilepsy, Alzheimer's disease, schizophrenia and depression); 2. Patients with multiple chronic diseases who cannot tolerate surgical anesthesia; 3. Severe heart, lung and kidney insufficiency; 4. Recent use history of cyclopol; 5. People with relevant drug allergy history and contraindications; 6. Patients with alcohol or drug abuse within 3 months; 7. Patients with QTC interval >= 450 ms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of bradycardia and hypotension during operation;Mean arterial pressure, heart rate, cardiac output, cardiac index, peripheral circulation resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time, intraoperative fluid infusion, blood loss, urine volume, recovery time;Postoperative complications (nausea and vomiting, intraoperative awareness, chills, respiratory depression, lethargy); | — |
Countries
China
Contacts
Public ContactZhang Min
Department of Anaesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Outcome results
None listed