Prostate cancer
Conditions
Interventions
Index test:[18F]AlF-Bi-PSMA PET/MR, [18F]PSMA-1007 PET/MR
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years old; 2. Patients with elevated PSA or other conditions that need to be considered for prostate malignancy (refer to the 2020 NCCN guidelines and the 2014 Chinese guidelines); 3. Patients with biochemical recurrence after radical prostatectomy (PSA>0.2); 4. Patients with castration-resistant prostate cancer; 5. Re-examination of prostate cancer patients after treatment; 6. Able to withstand magnetic resonance examination and have good compliance; 7. Sign the informed consent form for the inspection and undergo the [18F] AlF-Bi-PSMA PET/MR examination.
Exclusion criteria
Exclusion criteria: 1. Those with other malignant tumors during imaging; 2. Those who cannot lie flat for half an hour; 3. Suffering from claustrophobia or other psychiatric disorders; 4. Refusal or inability to tolerate prostate puncture examination halfway; 5. Those who are allergic to imaging agents; 6. Those with contraindications to MRI, such as MR-incompatible grafts (pacemakers, insulin pumps, cochlear implants, joint prostheses, etc.) in vivo); 7. Other cases where the investigator deems it inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of lesions and the SUV, SEN, SPE, ACC, AUC of ROC;Sensitivity;Diagnostic efficacy of prostate cancer;Specificity;positive predictive value; | — |
Countries
China
Contacts
Public ContactPengcheng Ran
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed