gastroesophageal reflux disease(GERD)with interstitial lung disease(ILD)
Conditions
Interventions
elderly gastroesophageal reflux disease (GERD) with interstitial lung disease (ILD):C-BLART (clip band ligation anti-refux therapy)
elderly gastroesophageal reflux disease (GERD) with interstitial lung disease (ILD):Drug therapy as a control
elderly gastroesophageal reflux disease (GERD):C-BLART (clip band ligation anti-refux therapy)
elderly gastroesophageal reflux disease (GERD):Drug therapy as a control
Sponsors
The First Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years old; 2. Meet the diagnostic criteria of GERD in 2020 "Chinese Expert Consensus Opinion on Gastroesophageal Reflux Disease"; 3. Meet the diagnostic criteria proposed by the American Thoracic Society (ATS) and the European Respiratory Society (ERS) for ILD in 2013; 4. Obtain informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with interstitial lung disease caused by other causes; 2. Patients with other diseases of the esophagus and lungs; 3. Patients who have undergone surgical lung biopsy or esophageal and gastric surgery; 4. Patients with end-stage heart, liver and kidney disease and other diseases that affect survival; 5. Patients who cannot tolerate endoscopic cardia coarctation; 6. Patients who have not obtained informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment success rate;DeMeester score;Number of long reflux episodes;Total number of reflux episodes;pH measurements: Total % time pH<4;LES residual pressure;pulmonary function; | — |
Secondary
| Measure | Time frame |
|---|---|
| LES resting pressure;FEV1/FVC;arterial partial pressure of oxygen; | — |
Countries
China
Contacts
Public ContactLinghu Enqiang
The First Medical Center of PLA General Hospital
Outcome results
None listed