Phenotype analysis of left ventricular-arterial coupling changes during the early resuscitation of septic shock and its relationship with prognosis

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300067793

Enrollment

Unknown

Registered

2023-01-28

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Interventions

Patients with septic shock:Not applicable

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Septic shock was diagnosed according to the Sepsis 3.0 Criteria; 2. Aged 18-90 years; 3. Informed consent was obtained.

Exclusion criteria

Exclusion criteria: 1. The terminal state that cannot be recovered (such as refractory shock) or death is expected within 24 hours; 2. Aortic valve disease, aortic valve replacement and other conditions that affect VTI measurement; 3. Poor image or intolerant to echocardiography examination; 4. ECMO, IABP or cardiac pacemaker and other cardiac assistive devices that affect the evaluation of ventricular-arterial coupling; 5. No central venous catheter or invasive arterial pressure monitoring; 6. Atrial fibrillation was occurring at the time of diagnosis of septic shock.

Design outcomes

Primary

Measure	Time frame
28-day mortality;	—

Secondary

Measure	Time frame
ICU mortality;the incidence of AKI at 7 days;duration of ICU stay;duration of inhospital stay;duration of invasive mechanical ventilating;	—

Countries

China

Contacts

Public ContactXiaoyang Zhou

HwaMei Hospital, University of Chinese Academy of Sciences

zhouxiaoyang_1990@163.com+86 182 6856 0726

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026