Nasopharyngeal carcinoma
Conditions
Interventions
treatment group:New Neck Prevention Irradiation Mode
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-75 years; 2. Patients are newly and histologically confirmed as NPC; 3. Patients are staged with T1-3N0-1M0 (American Joint Committee on Cancer, 8th edition); 4. The karnofsky performance status (KPS) score of patients are 70 or higher; 5. Patients have adequate hematological function (leukocyte count of at least 3.5 x 10^9/L, hemoglobin 90 g/L or higher, and a platelet count of at least 100 x 10^9/L), adequate renal function (creatinine <= 1.5 x upper limit of normal (ULN)), and adequate hepatic function (serum bilirubin <= 2.0 x ULN, and alanine aminotransferase and aspartate aminotransferase <= 2.5 x ULN).
Exclusion criteria
Exclusion criteria: 1. Patients have synchronous malignant tumor(s) at another site or a history of malignancies in the head and neck region underwent surgery, radiotherapy, or chemotherapy; 2. Patients have malignant disease for which treatment was ended 3cm; 6. Patients have mental or physical impairment causing them to be unable to fill out questionnaires; 7. Patients are participating in another clinical study; 8. Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-year Regional recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2-year overall survival rate;2-year distant metastasis free survival;2-year progression-free survival; | — |
Countries
China
Contacts
Public ContactShichuan Zhang
Sichuan Cancer Hospital
Outcome results
None listed