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The effectiveness and safety of blood flow restriction under different pressures combined with low-intensity resistance training in the treatment of knee osteoarthritis

The effectiveness and safety of blood flow restriction under different pressures combined with low-intensity resistance training in the treatment of knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067778
Enrollment
Unknown
Registered
2023-01-23
Start date
2023-02-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

Control group:They all took diclofenac sodium sustained-release tablets, produced by Beijing Novartis Pharmaceutical Co., Ltd., with a dose of 75 mg/tablet, once a day, for 12 consecutive weeks.
Experimental group 1:On the basis of the control group, 30% 1RM low intensity resistance training+30% blood flow restriction
Experimental group 2:On the basis of the control group, 30% 1RM low intensity resistance training+50% blood flow restriction
Experimental group 3:On the basis of the control group, 30% 1RM low intensity resistance training+80% blood flow restriction

Sponsors

Guizhou Orthopedic Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who meet the clinical evaluation criteria for knee osteoarthritis formulated by the American Rheumatological Association in 2005 and are diagnosed with unilateral or bilateral knee osteoarthritis; 2. Aged >= 40 years; 3. The knee joint on the affected side is graded 2-3 according to Kellgren & Lawrence (K&L); Visual Analog Scale Scoring (VAS) pain score 2 to 8 points, Lequesne Index score 5-12 points; 4. Have not participated in other clinical trials in the past 1 month; 5. Voluntarily join the test and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those who have experience in sports rehabilitation treatment or other similar exercises within 1 month before the experiment, such as qigong, yoga, etc.; 2. Intra-articular steroid injection or surgery in the past 3 months; 3. Severe dysfunction that leads to limited participation; 4. Intra-articular injection of hyaluronate in the past 6 months; 5. Exercise-induced or uncontrollable angina, acute or chronic renal failure, resting state of dyspnea, cardio-cerebral system diseases and other high-risk diseases have occurred within 3 months; 6. The Simple Mental Status Checklist (MMSE) < 23 points.

Design outcomes

Primary

MeasureTime frame
Isometric muscle strength;Visual analogue scale scoring;balance;Plantar stress test;Proprioception;—

Countries

China

Contacts

Public ContactFu Shenyu

Guizhou Orthopedic Hospital

2633782062@qq.com+86 157 2211 8140

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026