Oral mucositis
Conditions
Interventions
Experimental group:Huoshan Dendrobium Zengye Jiedu Formula
Control group:Kangfuxin liquid
Sponsors
The First Department of Oncology, The First Affiliated Hospital of Anhui University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The age is 18-80 years old, regardless of gender; 2. Patients with oral mucositis diagnosed clinically; 3. Patients with advanced malignant tumors confirmed by cytology or histology pathology are head and neck tumors (including nasopharyngeal cancer, esophageal cancer, etc.), lung cancer, stomach cancer, ovarian cancer, breast cancer, cervical cancer, etc. TNM stage is ? - ?; ECOG score 0~1; The expected survival period is more than 6 months; 4. Those who have experienced radiotherapy or chemotherapy or concurrent radiotherapy and chemotherapy (the chemotherapy plan includes at least one or more of cyclophosphamide, methotrexate, nitrogen mustard, cisplatin, gemcitabine, cytarabine, vinblastine, podophyllotoxin, paclitaxel and other drugs) shall undergo chemotherapy; 5. The patient has clear consciousness, language expression ability or reading ability, can communicate normally, and can cooperate to complete the assessment; 6. Volunteer to join the study, the patient has good compliance, can understand the situation of the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who are known to be allergic to the components of this drug; 2. Those who do not conform to the diagnosis or whose diagnosis is unclear; 3. Patients with primary immunodeficiency disease and other serious infectious diseases, and patients treated with immunomodulator; 4. Patients with abnormal blood routine, liver function and renal function; 5. Pregnant or lactating women, and people with mental disorders; 6. Poor compliance; 7. For other reasons, the researcher thinks it is not suitable to participate in this study; 8. Patients who have taken other trial drugs or are in other clinical trials in the past month cannot be selected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain digital scoring;Inappropriate score;WHO classification of oral mucositis;Core scale score of quality of life for cancer patients;Immune function test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor markers;routine blood test; | — |
Countries
China
Contacts
Public ContactZhu Yongfu
The First Affiliated Hospital of Anhui University of Chinese Medicine
Outcome results
None listed