Cervical degenerative disease
Conditions
Interventions
ACXF:Perform ACXF operation
ACCF:Perform ACCF operation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Patients with cervical spondylosis diagnosed clearly according to clinical symptoms, signs and imaging findings; 3. After standard conservative treatment, the patient is ineffective or the symptoms are gradually aggravated, affecting daily life and work, and needs to undergo ACCF or ACXF surgery; 4. The surgical segment is between C3/4 and C7T1; 5. Be able to fully comply with the contents of this study protocol psychologically and physiologically, and cooperate with the scheduled treatment plan, fill in the questionnaire form and follow up; 6. After the patient signs the informed consent, it means that the patient has known and agreed to carry out the relevant aspects of this study. The above inclusion standards are international common standards to ensure rationality and feasibility.
Exclusion criteria
Exclusion criteria: 1. Previous history of cervical spine surgery and adjacent segmental bone fusion; 2. Cervical vertebra development deformity, spinal fracture, severe osteoporosis or history of bone metabolic disease; 3. Local infection and ulceration of neck skin, systemic inflammatory disease, rheumatoid arthritis, uncontrolled diabetes, malignant tumor, active hepatitis, etc.; 4. People with mental illness or mental disorder; 5. The general condition is poor, and important organs are suffering from serious diseases and cannot tolerate surgery; 6. Known to suffer from infectious diseases such as AIDS, syphilis, etc.; 7. He has received daily immunosuppressive therapy for more than 1 month in the past 12 months; 8. Allergic to implant materials (PPE K or titanium alloy); 9. Severe obesity, drug abuse history; 10. Pregnancy or pregnancy plan during the study period; 11. He is participating in other studies that may affect the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Japanese Orthopaedic Association Scores;Neck Disabilitv Index socre;visual analogue scale for arm and neck; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation duration time;Bleeding durning surgery;fusion rate;Imaging complications;Total complications after cervical surgery; | — |
Countries
China
Contacts
Public ContactChen Ding
West China Hospital, Sichuan University
Outcome results
None listed