Gut Microbiota Studies of Patients in Neuro-Intensive Care Unit

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067752

Enrollment

Unknown

Registered

2023-01-20

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients in Neuro-Intensive Care Unit

Interventions

PHGG Group:PHGG

Routine enteral nutrition Group:NA

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The patient has a clear history of trauma; 2. Aged 18 to 70 years; 3. Evaluation of GCS score of 3 to 12 after admission to the hospital; 4. Time interval between injury and admission < 24h; 5. Patients accept Clinical diagnosis by CT, MRI after admission, etc.; 6. Obtain the consent of family members; 7. Pass ethical review.

Exclusion criteria

Exclusion criteria: 1. Patients with previous gastrointestinal diseases or previous gastrointestinal surgery; 2. Antibiotics, proton pump inhibitors and probiotics used within 1 month; 3. Previous brain injury or surgery; 4. Past psychiatric history and current treatment with psychotropic drugs; 5. Other diseases such as autoimmune diseases, hypothyroidism, Parkinson's disease, and previous stroke history; 6. Family members refuse to sign their consent.

Design outcomes

Primary

Measure	Time frame
intestinal microbiome;Glasgow Outcome Scale;28 days mortality;	—

Secondary

Measure	Time frame
Hospital stay;	—

Countries

China

Contacts

Public ContactYuping Li

Clinical Medical College of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou University

yupingli@yzu.edu.cn+86 18051062519

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026