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The mechanisms of supplementing Qi, nourishing Yin and promoting blood circulation Chinese Herbs on intervention of diabetic Atherosclerosis based on glycosylation of AMPK/SIRT1/PGC-1 alpha mediated NETs formation

The mechanisms of supplementing Qi, nourishing Yin and promoting blood circulation Chinese Herbs on intervention of diabetic Atherosclerosis based on glycosylation of AMPK/SIRT1/PGC-1 alpha mediated NETs formation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067748
Enrollment
Unknown
Registered
2023-01-20
Start date
2023-01-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis in type 2 diabetes

Interventions

Atherosclerosis group:N/A
Type 2 diabetes patients with atherosclerosis:N/A
Healthy control group:N/A

Sponsors

Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The age range of subjects is 18-70 years old; 2. Meet the diagnostic criteria for type 2 diabetes and atherosclerosis; 3. Volunteer to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Type 1 diabetes or acute complications of diabetes; 2. Those who are in the acute stage of cerebrovascular disease, or have had serious cardiovascular and cerebrovascular diseases in recent 3 months; 3. He has been treated with other hormones (non insulin) and other drugs that affect blood glucose in recent 2 months; 4. Long term alcohol abuse, drug dependence or mental illness; 5. Women in pregnancy or lactation; 6. Patients with severe diseases of digestive tract, nervous system and blood system.

Design outcomes

Primary

MeasureTime frame
Fasting blood glucose;glycosylated hemoglobin;total cholesterol;triglyceride;High density lipoprotein cholesterol, HDL-C;Low-density lipoprotein cholesterol, LDL-C;routine blood test;Alanine aminotransferase;Creatinine;

Countries

China

Contacts

Public ContactZhao Junnan

Xiyuan Hospital, China Academy of Chinese Medical Sciences

13240050425@163.com+86 132 4005 0425

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026