Rectal cancer with lateral lymph node metastasis
Conditions
Interventions
Control group:Laparoscopic total mesorectal resection with lateral lymph node dissection
Experimental group:Laparoscopic total mesorectal resection with lateral lymph node dissection guided by indocyanine green
Sponsors
The Second Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Rectal cancer (located below peritoneal reflection); 2. Preoperative MRI showed that the short diameter of rectal lymph nodes is >= 10mm; 3. Indications for laparoscopic surgery; 4. Non-multiple primary or recurrent cancer; 5. No preoperative chemoradiotherapy; 6. No distant metastasis; 7. No intestinal obstruction, intestinal perforation and other complications.
Exclusion criteria
Exclusion criteria: 1. Intestinal obstruction, intestinal perforation and other complications which require emergency surgery; 2. Recurrent or multiple primary colorectal cancer; 3. Contraindications for laparoscopic surgery; 4. Lateral metastatic lymph nodes invaded the piriformis muscle, sacral plexus nerve or circumvented external iliac arteriovenous; 5. Patients with lateral lymph node metastasis accompanied by distant metastasis could not achieve R0 resection; 6. The primary tumor could not be resected with R0; 7. There was extensive lateral and retroperitoneal lymph node metastasis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early (30 days) complication rate;Number of postoperative lateral lymph nodes dissected;Number of postoperative lateral lymph node metastasized; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of first anal exhaust after operation;Postoperative hospital stay;Number of postoperative lymphatic fistula cases;Number of postoperative abdominal hemorrhage cases;Number of postoperative urinary dysfunction cases; | — |
Countries
China
Contacts
Public ContactChuying Wu
The Second Affiliated Hospital of Fujian Medical University
Outcome results
None listed