Hypertension
Conditions
Interventions
newly diagnosed grade I hypertension:None
any hypertension with stable medication:None
normotension:None
Sponsors
Beijing Anzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Older than 18; 2. Newly diagnosed grade I hypertension (SBP/DBP >130/80mmHg and = 15 times/hour in polysomnography.
Exclusion criteria
Exclusion criteria: 1. Previous diagnosis of OSA with CPAP treatment presently; 2. Secondary hypertension caused by factors other than OSA,eg. renal artery stenosis, chronic kidney disease, Cushing syndrome, etc.; 3. Unstable condition, eg. hypertensive crisis; 4. Rheumatic immune diseases and malignant tumors; 5. Major arterial diseases (such as arthritis, arterial dissection, aneurysm, etc.); 6. Diseases that influencing the measurement of blood pressure (such as atrial fibrillation, upper limb vascular diseases); 7. Family history of early-onset hypertension; 8. The current type and dosage of anti-hypertensive agents are unstable, and blood pressure fluctuates greatly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Sleep;arterial function; | — |
Secondary
| Measure | Time frame |
|---|---|
| catecholamine;The renin angiotensin aldosterone system;Single nucleotide;microalbunminuria; | — |
Countries
China
Contacts
Public ContactXie Jiang
Beijing Anzhen Hospital
Outcome results
None listed