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Predictive value of cardiac output changes induced by postural changes on volume responsiveness in critically ill patients

Predictive value of cardiac output changes induced by postural changes on volume responsiveness in critically ill patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067694
Enrollment
Unknown
Registered
2023-01-18
Start date
2023-01-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute circulatory failure

Interventions

Gold Standard: An increase of >=15% in SVI monitored by PiCCO after 250ml intravenous infusion of 4% albumin within 10 minutes was considered to be volume responsive.
Index test:positional change

Sponsors

Tianjin Third Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Age >=18 years; Hemodynamic monitoring is being performed using a PiCCO device; Presence of at least one of the following criteria for tissue hypoperfusion: Systolic blood pressure 50 mmHg in hypertensive patients), or the need for vasoactive drugs (dopamine > 5µg/kg/min or norepinephrine), arterial lactate > 2mmol/L, urine volume 100 beats /min), Prolonged capillary refill time or skin patchy.

Exclusion criteria

Exclusion criteria: The presence of contraindications to rehydration tests (e.g., evidence of acute coronary syndrome, heart failure, cardiogenic shock, or volume overload); Pregnancy; Intracranial hypertension or risk of intracranial hypertension (e.g. cerebrovascular accident, craniocerebral trauma); Wear pressure stockings.

Design outcomes

Primary

MeasureTime frame
cardiac index;stroke volume index;

Secondary

MeasureTime frame
Central venous pressure;Pulse pressure variation;Stroke volume variation;

Countries

China

Contacts

Public ContactZhiyong Wang

Tianjin Third Central Hospital

waizh1018@126.com+86 22 84112109

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026