pigmentation
Conditions
Interventions
Test product group:Melanization and apply test product
Negative control group:Melanization
Positive control group:Melanization and application of ascorbic acid
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.18-60 years old, healthy male or female; 2. The ITA ° value of skin color at the test site is 20 ° - 41 °; 3. No allergic disease, no history of allergy to cosmetics or other external preparations; 4. No history of photosensitive diseases in the past, and no drugs that affect photosensitivity have been used in the near future; 5. The skin of the tested part should be free of pigmentation, inflammation, scar, pigmented nevus, hirsutism, etc; 6. Those who can accept the tanning of the skin in the test area with artificial light source; 7. Those who can understand the test process, voluntarily participate in the test and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women, or those who have a pregnancy preparation plan recently; 2. Have a history of psoriasis, eczema, atopic dermatitis, severe acne and other skin diseases; 3. Those who have taken oral or external corticosteroids and other anti-inflammatory drugs in the past month; 4. Those who have taken orally or externally used any products or drugs (such as hydroquinone preparations) that affect the skin color in the past 2 months; 5. Those who have participated in the same type of test in the past 3 months or participated in the same type of test 3 months ago, but the skin melanization mark of the test site has not completely disappeared; 6. Those who have participated in other clinical trials in recent 2 months; 7. Other persons who are not suitable for the trial according to the clinical evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| melanin index;individual type angle;visual skin color assessment; | — |
Countries
China
Contacts
Public ContactLi Li
Outcome results
None listed